Brk Activates Rac1 and Promotes Cell Migration and Invasion by Phosphorylating Paxillin

Brk (for breast tumor kinase) is a nonreceptor tyrosine kinase containing SH3, SH2, and tyrosine kinase catalytic domains. Brk was originally identified from a human metastatic breast tumor, and its overexpression is frequently observed in breast cancer and several other cancer types. However, the m...

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Autori principali: Chen, Hsin-Yi, Shen, Che-Hung, Tsai, Yuh-Tyng, Lin, Feng-Chi, Huang, Yuan-Ping, Chen, Ruey-Hwa
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Cell Growth and Development
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC533963/
https://ncbi.nlm.nih.gov/pubmed/15572663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10558-10572.2004
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