Brk Activates Rac1 and Promotes Cell Migration and Invasion by Phosphorylating Paxillin

Brk (for breast tumor kinase) is a nonreceptor tyrosine kinase containing SH3, SH2, and tyrosine kinase catalytic domains. Brk was originally identified from a human metastatic breast tumor, and its overexpression is frequently observed in breast cancer and several other cancer types. However, the m...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Chen, Hsin-Yi, Shen, Che-Hung, Tsai, Yuh-Tyng, Lin, Feng-Chi, Huang, Yuan-Ping, Chen, Ruey-Hwa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2004
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC533963/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15572663/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.24.10558-10572.2004
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