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Brk Activates Rac1 and Promotes Cell Migration and Invasion by Phosphorylating Paxillin
Brk (for breast tumor kinase) is a nonreceptor tyrosine kinase containing SH3, SH2, and tyrosine kinase catalytic domains. Brk was originally identified from a human metastatic breast tumor, and its overexpression is frequently observed in breast cancer and several other cancer types. However, the m...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC533963/ https://ncbi.nlm.nih.gov/pubmed/15572663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10558-10572.2004 |
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