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Cooperative Regulation of the Cell Division Cycle by the Protein Kinases RAF and AKT
The RAS-activated RAF→MEK→extracellular signal-regulated kinase (ERK) and phosphatidylinositol 3′-kinase (PI3′-kinase)→PDK1→AKT signaling pathways are believed to cooperate to promote the proliferation of normal cells and the aberrant proliferation of cancer cells. To explore the mechanisms that und...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC533961/ https://ncbi.nlm.nih.gov/pubmed/15572689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10868-10881.2004 |
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