Cooperative Regulation of the Cell Division Cycle by the Protein Kinases RAF and AKT

The RAS-activated RAF→MEK→extracellular signal-regulated kinase (ERK) and phosphatidylinositol 3′-kinase (PI3′-kinase)→PDK1→AKT signaling pathways are believed to cooperate to promote the proliferation of normal cells and the aberrant proliferation of cancer cells. To explore the mechanisms that und...

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Detalhes bibliográficos
Main Authors: Mirza, Amer M., Gysin, Stephan, Malek, Nisar, Nakayama, Kei-ichi, Roberts, James M., McMahon, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC533961/
https://ncbi.nlm.nih.gov/pubmed/15572689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10868-10881.2004
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