Identification of Significant Pathways Induced by PAX5 Haploinsufficiency Based on Protein-Protein Interaction Networks and Cluster Analysis in Raji Cell Line

PAX5 encodes a transcription factor essential for B-cell differentiation, and PAX5 haploinsufficiency is involved in tumorigenesis. There were few studies on how PAX5 haploinsufficiency regulated genes expression to promote tumorigenesis. In this study, we constructed the cell model of PAX5 haploins...

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Bibliografiske detaljer
Udgivet i:Biomed Res Int
Main Authors: Gu, Jia, Li, TongJuan, Zhao, Lei, Liang, Xue, Fu, Xing, Wang, Jue, Shang, Zhen, Huang, Wei, Zhou, Jianfeng
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339483/
https://ncbi.nlm.nih.gov/pubmed/28316978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5326370
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