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Targeted disruption of Pax1 defines its null phenotype and proves haploinsufficiency

The murine paired box-containing gene Pax1 is required for normal development of the vertebral column, the sternum, and the scapula. Previous studies have shown that three natural Pax1 mouse mutants, the undulated alleles, exhibit phenotypes of different severity in these skeletal elements. Neverthe...

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Autors principals: Wilm, Bettina, Dahl, Edgar, Peters, Heiko, Balling, Rudi, Imai, Kenji
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC21138/
https://ncbi.nlm.nih.gov/pubmed/9671740
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