Targeted disruption of Pax1 defines its null phenotype and proves haploinsufficiency
The murine paired box-containing gene Pax1 is required for normal development of the vertebral column, the sternum, and the scapula. Previous studies have shown that three natural Pax1 mouse mutants, the undulated alleles, exhibit phenotypes of different severity in these skeletal elements. Neverthe...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1998
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21138/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9671740/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.15.8692 |
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