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Antiviral Effects of Human Immunodeficiency Virus Type 1-Specific Small Interfering RNAs against Targets Conserved in Select Neurotropic Viral Strains

RNA interference, a natural biological phenomenon mediated by small interfering RNAs (siRNAs), has been demonstrated in recent studies to be an effective strategy against human immunodeficiency virus type 1 (HIV-1). In the present study, we used 21-bp chemically synthesized siRNA duplexes whose sequ...

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Hlavní autoři: Dave, Rajnish S., Pomerantz, Roger J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC533941/
https://ncbi.nlm.nih.gov/pubmed/15564478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.13687-13696.2004
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