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Broad-Spectrum Antiviral Activity of Small Interfering RNA Targeting the Conserved RNA Termini of Lassa Virus

Small interfering RNAs targeting the conserved RNA termini upstream of NP and L gene were found to reduce reporter gene expression from Lassa virus replicon and Lassa virus mRNA expression construct and to inhibit replication of different Lassa virus strains, lymphocytic choriomeningitis virus, and...

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Autors principals: Müller, Stefanie, Günther, Stephan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891391/
https://ncbi.nlm.nih.gov/pubmed/17371814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01368-06
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