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Broad-Spectrum Antiviral Activity of Small Interfering RNA Targeting the Conserved RNA Termini of Lassa Virus

Small interfering RNAs targeting the conserved RNA termini upstream of NP and L gene were found to reduce reporter gene expression from Lassa virus replicon and Lassa virus mRNA expression construct and to inhibit replication of different Lassa virus strains, lymphocytic choriomeningitis virus, and...

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Detalhes bibliográficos
Main Authors: Müller, Stefanie, Günther, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891391/
https://ncbi.nlm.nih.gov/pubmed/17371814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01368-06
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