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Evaluation of Rint1 as a modifier of intestinal tumorigenesis and cancer risk

The Rad50 Interacting Protein 1 (Rint1) influences cellular homeostasis through maintenance of endoplasmic reticulum, Golgi and centrosome integrity and regulation of vesicle transport, autophagy and the G(2)/M checkpoint. Rint1 has been postulated to function as a tumor suppressor as well as an onc...

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Pubblicato in:PLoS One
Autori principali: Otterpohl, Karla L., Gould, Karen A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339343/
https://ncbi.nlm.nih.gov/pubmed/28264000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172247
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