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Identification of Severe Acute Respiratory Syndrome Coronavirus Replicase Products and Characterization of Papain-Like Protease Activity

Gene 1 of the coronavirus associated with severe acute respiratory syndrome (SARS) encodes replicase polyproteins that are predicted to be processed into 16 nonstructural proteins (nsps 1 to 16) by two viral proteases, a papain-like protease (PLpro) and a 3C-like protease (3CLpro). Here, we identify...

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Библиографические подробности
Опубликовано в::J Virol
Главные авторы: Harcourt, Brian H., Jukneliene, Dalia, Kanjanahaluethai, Amornrat, Bechill, John, Severson, Kari M., Smith, Catherine M., Rota, Paul A., Baker, Susan C.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2004
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC533933/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15564471/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.24.13600-13612.2004
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