ComE, an Essential Response Regulator, Negatively Regulates the Expression of the Capsular Polysaccharide Locus and Attenuates the Bacterial Virulence in Streptococcus pneumoniae

The capsular polysaccharide (CPS) of Streptococcus pneumoniae is the main virulence factors required for effective colonization and invasive disease. The capacity to regulate CPS production at the transcriptional level is critical for the survival of S. pneumoniae in different host niches, but littl...

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Bibliografske podrobnosti
izdano v:Front Microbiol
Main Authors: Zheng, Yuqiang, Zhang, Xuemei, Wang, Xiaofang, Wang, Libin, Zhang, Jinghui, Yin, Yibing
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Microbiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339220/
https://ncbi.nlm.nih.gov/pubmed/28326061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00277
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