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ComE, an Essential Response Regulator, Negatively Regulates the Expression of the Capsular Polysaccharide Locus and Attenuates the Bacterial Virulence in Streptococcus pneumoniae

The capsular polysaccharide (CPS) of Streptococcus pneumoniae is the main virulence factors required for effective colonization and invasive disease. The capacity to regulate CPS production at the transcriptional level is critical for the survival of S. pneumoniae in different host niches, but littl...

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Détails bibliographiques
Publié dans:Front Microbiol
Auteurs principaux: Zheng, Yuqiang, Zhang, Xuemei, Wang, Xiaofang, Wang, Libin, Zhang, Jinghui, Yin, Yibing
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339220/
https://ncbi.nlm.nih.gov/pubmed/28326061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00277
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