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Clarifying the molecular mechanism associated with carfilzomib resistance in human multiple myeloma using microarray gene expression profile and genetic interaction network

Carfilzomib is a Food and Drug Administration-approved selective proteasome inhibitor for patients with multiple myeloma (MM). However, recent studies indicate that MM cells still develop resistance to carfilzomib, and the molecular mechanisms associated with carfilzomib resistance have not been stu...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Zheng, Zhihong, Liu, Tingbo, Zheng, Jing, Hu, Jianda
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338971/
https://ncbi.nlm.nih.gov/pubmed/28280367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S130742
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