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Clarifying the molecular mechanism associated with carfilzomib resistance in human multiple myeloma using microarray gene expression profile and genetic interaction network

Carfilzomib is a Food and Drug Administration-approved selective proteasome inhibitor for patients with multiple myeloma (MM). However, recent studies indicate that MM cells still develop resistance to carfilzomib, and the molecular mechanisms associated with carfilzomib resistance have not been stu...

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Publicado en:Onco Targets Ther
Autores principales: Zheng, Zhihong, Liu, Tingbo, Zheng, Jing, Hu, Jianda
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338971/
https://ncbi.nlm.nih.gov/pubmed/28280367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S130742
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