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Clarifying the molecular mechanism associated with carfilzomib resistance in human multiple myeloma using microarray gene expression profile and genetic interaction network

Carfilzomib is a Food and Drug Administration-approved selective proteasome inhibitor for patients with multiple myeloma (MM). However, recent studies indicate that MM cells still develop resistance to carfilzomib, and the molecular mechanisms associated with carfilzomib resistance have not been stu...

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Pubblicato in:Onco Targets Ther
Autori principali: Zheng, Zhihong, Liu, Tingbo, Zheng, Jing, Hu, Jianda
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338971/
https://ncbi.nlm.nih.gov/pubmed/28280367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S130742
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