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Identification and validation of regulatory SNPs that modulate transcription factor chromatin binding and gene expression in prostate cancer

Prostate cancer (PCa) is the second most common solid tumor for cancer related deaths in American men. Genome wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) associated with the increased risk of PCa. Because most of the susceptibility SNPs are located in nonco...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Jin, Hong-Jian, Jung, Segun, DebRoy, Auditi R., Davuluri, Ramana V.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338917/
https://ncbi.nlm.nih.gov/pubmed/27409348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10520
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