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Transcriptional Control by PARP-1: Chromatin Modulation, Enhancer-binding, Coregulation, and Insulation
The regulation of gene expression requires a wide array of protein factors that can modulate chromatin structure, act at enhancers, function as transcriptional coregulators, or regulate insulator function. Poly(ADP-ribose) polymerase-1 (PARP-1), an abundant and ubiquitous nuclear enzyme that catalyz...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518631/ https://ncbi.nlm.nih.gov/pubmed/18450439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2008.03.006 |
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