In Vitro Characterization of a Simian Immunodeficiency Virus-Human Immunodeficiency Virus (HIV) Chimera Expressing HIV Type 1 Reverse Transcriptase To Study Antiviral Resistance in Pigtail Macaques

Antiviral resistance is a significant obstacle in the treatment of human immunodeficiency virus type 1 (HIV-1)-infected individuals. Because nonnucleoside reverse transcriptase inhibitors (NNRTIs) specifically target HIV-1 reverse transcriptase (RT) and do not effectively inhibit simian immunodefici...

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Autores principales: Ambrose, Zandrea, Boltz, Valerie, Palmer, Sarah, Coffin, John M., Hughes, Stephen H., KewalRamani, Vineet N.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC533891/
https://ncbi.nlm.nih.gov/pubmed/15564466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.13553-13561.2004
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