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Mass Defect-Based N,N-Dimethyl Leucine Labels for Quantitative Proteomics and Amine Metabolomics of Pancreatic Cancer Cells

Mass spectrometry-based stable isotope labeling has become a key technology for protein and small-molecule analyses. We developed a multiplexed quantification method for simultaneous proteomics and amine metabolomics analyses via nano reversed-phase liquid chromatography–tandem mass spectrometry (na...

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發表在:Anal Chem
Main Authors: Hao, Ling, Johnson, Jillian, Lietz, Christopher B., Buchberger, Amanda, Frost, Dustin, Kao, W. John, Li, Lingjun
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338727/
https://ncbi.nlm.nih.gov/pubmed/28194987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b03482
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