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Investigations of human myosin VI targeting using optogenetically controlled cargo loading

Myosins play countless critical roles in the cell, each requiring it to be activated at a specific location and time. To control myosin VI with this specificity, we created an optogenetic tool for activating myosin VI by fusing the light-sensitive Avena sativa phototropin1 LOV2 domain to a peptide f...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: French, Alexander R., Sosnick, Tobin R., Rock, Ronald S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338553/
https://ncbi.nlm.nih.gov/pubmed/28193860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614716114
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