Phosphorylation of αB-crystallin supports reactive astrogliosis in demyelination

The small heat shock protein αB-crystallin (CRYAB) has been implicated in multiple sclerosis (MS) pathogenesis. Earlier studies have indicated that CRYAB inhibits inflammation and attenuates clinical disease when administered in the experimental autoimmune encephalomyelitis model of MS. In this stud...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Kuipers, Hedwich F., Yoon, Jane, van Horssen, Jack, Han, May H., Bollyky, Paul L., Palmer, Theo D., Steinman, Lawrence
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2017
Teme:
PNAS Plus
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338510/
https://ncbi.nlm.nih.gov/pubmed/28196893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621314114
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