Phosphorylation of αB-crystallin supports reactive astrogliosis in demyelination

The small heat shock protein αB-crystallin (CRYAB) has been implicated in multiple sclerosis (MS) pathogenesis. Earlier studies have indicated that CRYAB inhibits inflammation and attenuates clinical disease when administered in the experimental autoimmune encephalomyelitis model of MS. In this stud...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Kuipers, Hedwich F., Yoon, Jane, van Horssen, Jack, Han, May H., Bollyky, Paul L., Palmer, Theo D., Steinman, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338510/
https://ncbi.nlm.nih.gov/pubmed/28196893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621314114
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