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High-resolution imaging and quantification of plasma membrane cholesterol by NanoSIMS

Cholesterol is a crucial lipid within the plasma membrane of mammalian cells. Recent biochemical studies showed that one pool of cholesterol in the plasma membrane is “accessible” to binding by a modified version of the cytolysin perfringolysin O (PFO*), whereas another pool is sequestered by sphing...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: He, Cuiwen, Hu, Xuchen, Jung, Rachel S., Weston, Thomas A., Sandoval, Norma P., Tontonoz, Peter, Kilburn, Matthew R., Fong, Loren G., Young, Stephen G., Jiang, Haibo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338444/
https://ncbi.nlm.nih.gov/pubmed/28167768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621432114
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