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Hippo signaling promotes JNK-dependent cell migration

Overwhelming studies show that dysregulation of the Hippo pathway is positively correlated with cell proliferation, growth, and tumorigenesis. Paradoxically, the detailed molecular roles of the Hippo pathway in cell invasion remain debatable. Using a Drosophila invasion model in wing epithelium, we...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ma, Xianjue, Wang, Hongxiang, Ji, Jiansong, Xu, Wenyan, Sun, Yihao, Li, Wenzhe, Zhang, Xiaoping, Chen, Juxiang, Xue, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338425/
https://ncbi.nlm.nih.gov/pubmed/28174264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621359114
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