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Impaired Hippo signaling promotes Rho1–JNK-dependent growth
The Hippo and c-Jun N-terminal kinase (JNK) pathway both regulate growth and contribute to tumorigenesis when dysregulated. Whereas the Hippo pathway acts via the transcription coactivator Yki/YAP to regulate target gene expression, JNK signaling, triggered by various modulators including Rho GTPase...
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| Foilsithe in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
National Academy of Sciences
2015
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4313816/ https://ncbi.nlm.nih.gov/pubmed/25583514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415020112 |
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