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Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry
S-acylation is a major posttranslational modification, catalyzed by the zinc finger DHHC domain containing (zDHHC) enzyme family. S-acylated proteins can be modified by different fatty acids; however, very little is known about how zDHHC enzymes contribute to acyl chain heterogeneity. Here, we used...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338407/ https://ncbi.nlm.nih.gov/pubmed/28167757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612254114 |
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