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ACSS2-mediated acetyl-CoA synthesis from acetate is necessary for human cytomegalovirus infection
Recent studies have shown that human cytomegalovirus (HCMV) can induce a robust increase in lipid synthesis which is critical for the success of infection. In mammalian cells the central precursor for lipid biosynthesis, cytosolic acetyl CoA (Ac-CoA), is produced by ATP-citrate lyase (ACLY) from mit...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338361/ https://ncbi.nlm.nih.gov/pubmed/28167750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614268114 |
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