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Role of a circadian-relevant gene NR1D1 in brain development: possible involvement in the pathophysiology of autism spectrum disorders

In our previous study, we screened autism spectrum disorder (ASD) patients with and without sleep disorders for mutations in the coding regions of circadian-relevant genes, and detected mutations in several clock genes including NR1D1. Here, we further screened ASD patients for NR1D1 mutations and i...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Goto, Masahide, Mizuno, Makoto, Matsumoto, Ayumi, Yang, Zhiliang, Jimbo, Eriko F., Tabata, Hidenori, Yamagata, Takanori, Nagata, Koh-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338261/
https://ncbi.nlm.nih.gov/pubmed/28262759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43945
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