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TCRβ repertoire of CD4(+) and CD8(+) T cells is distinct in richness, distribution, and CDR3 amino acid composition
The TCR repertoire serves as a reservoir of TCRs for recognizing all potential pathogens. Two major types of T cells, CD4(+) and CD8(+), that use the same genetic elements and process to generate a functional TCR differ in their recognition of peptide bound to MHC class II and I, respectively. Howev...
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| 發表在: | J Leukoc Biol |
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| Main Authors: | , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Society for Leukocyte Biology
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338248/ https://ncbi.nlm.nih.gov/pubmed/26394815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.6A0215-071RR |
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