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The pro-inflammatory signalling regulator Stat4 promotes vasculogenesis of great vessels derived from endothelial precursors

Vasculogenic defects of great vessels (GVs) are a major cause of congenital cardiovascular diseases. However, genetic regulators of endothelial precursors in GV vasculogenesis remain largely unknown. Here we show that Stat4, a transcription factor known for its regulatory role of pro-inflammatory si...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Meng, Zhao-Zheng, Liu, Wei, Xia, Yu, Yin, Hui-Min, Zhang, Chi-Yuan, Su, Dan, Yan, Li-Feng, Gu, Ai-Hua, Zhou, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338034/
https://ncbi.nlm.nih.gov/pubmed/28256502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14640
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