Epigenetic Activation of Pro-angiogenic Signaling Pathways in Human Endothelial Progenitors Increases Vasculogenesis

Human endothelial colony-forming cells (ECFCs) represent a promising source of adult stem cells for vascular repair, yet their regenerative capacity is limited. Here, we set out to understand the molecular mechanism restricting the repair function of ECFCs. We found that key pro-angiogenic pathways...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Fraineau, Sylvain, Palii, Carmen G., McNeill, Brian, Ritso, Morten, Shelley, William C., Prasain, Nutan, Chu, Alphonse, Vion, Elodie, Rieck, Kristy, Nilufar, Sharmin, Perkins, Theodore J., Rudnicki, Michael A., Allan, David S., Yoder, Mervin C., Suuronen, Erik J., Brand, Marjorie
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830028/
https://ncbi.nlm.nih.gov/pubmed/29033304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.09.009
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