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A selective and label-free strategy for rapid screening of telomere-binding Ligands via fluorescence regulation of DNA/silver nanocluster

Herein, the conformational switch of G-rich oligonucleotide (GDNA) demonstrated the obvious functional switch of GDNA which was found to significantly affect the fluorescence of the in-situ synthesized DNA/silver nanocluster (DNA-AgNC) in homogeneous solution. We envisioned that the allosteric inter...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cheng, Rui, Xu, Jing, Zhang, Xiafei, Shi, Zhilu, Zhang, Qi, Jin, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338008/
https://ncbi.nlm.nih.gov/pubmed/28262705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42629
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