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Epigenetic modifications of interleukin-6 in synovial fibroblasts from osteoarthritis patients

Osteoarthritis (OA) is the most common degenerative disease of the synovial joint. The synovial membrane is responsible for the inflammatory reaction leading to the secretion of macrophage-derived pro-inflammatory cytokines, such as IL-6. Suppressing IL-6 over-expression in synovial fibroblasts (SF)...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yang, Fei, Zhou, Song, Wang, Chuandong, Huang, Yan, Li, Huiwu, Wang, You, Zhu, Zhenan, Tang, Jian, Yan, Mengning
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337936/
https://ncbi.nlm.nih.gov/pubmed/28262826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43592
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