Multiple expression cassette exchange via TP901‐1, R4, and Bxb1 integrase systems on a mouse artificial chromosome

The site‐specific excision of a target DNA sequence for genetic knockout or lineage tracing is a powerful tool for investigating biological systems. Currently, site‐specific recombinases (SSRs), such as Cre or Flp recombination target cassettes, have been successfully excised or inverted by a single...

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Detalles Bibliográficos
Publicado en:FEBS Open Bio
Autores principales: Tomimatsu, Kosuke, Kokura, Kenji, Nishida, Tadashi, Yoshimura, Yuki, Kazuki, Yasuhiro, Narita, Masashi, Oshimura, Mitsuo, Ohbayashi, Tetsuya
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337897/
https://ncbi.nlm.nih.gov/pubmed/28286726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12169
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