CD49a Expression Defines Tissue-Resident CD8(+) T Cells Poised for Cytotoxic Function in Human Skin

Tissue-resident memory T (Trm) cells form a heterogeneous population that provides localized protection against pathogens. Here, we identify CD49a as a marker that differentiates CD8(+) Trm cells on a compartmental and functional basis. In human skin epithelia, CD8(+)CD49a(+) Trm cells produced inte...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Cheuk, Stanley, Schlums, Heinrich, Gallais Sérézal, Irène, Martini, Elisa, Chiang, Samuel C., Marquardt, Nicole, Gibbs, Anna, Detlofsson, Ebba, Introini, Andrea, Forkel, Marianne, Höög, Charlotte, Tjernlund, Annelie, Michaëlsson, Jakob, Folkersen, Lasse, Mjösberg, Jenny, Blomqvist, Lennart, Ehrström, Marcus, Ståhle, Mona, Bryceson, Yenan T., Eidsmo, Liv
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337619/
https://ncbi.nlm.nih.gov/pubmed/28214226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2017.01.009
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