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Splenic accumulation of IL-10 mRNA in T cells distinct from CD4(+)CD25(+) (Foxp3) regulatory T cells in human visceral leishmaniasis

Visceral leishmaniasis (VL) is a life-threatening disease characterized by uncontrolled parasitization of the spleen, liver, and bone marrow. Interleukin (IL)-10 has been implicated in the suppression of host immunity in human VL based on the elevated levels of IL-10 observed in plasma and lesional...

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Detalhes bibliográficos
Main Authors: Nylén, Susanne, Maurya, Radheshyam, Eidsmo, Liv, Manandhar, Krishna Das, Sundar, Shyam, Sacks, David
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118563/
https://ncbi.nlm.nih.gov/pubmed/17389235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061141
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