Spoxazomicin D and Oxachelin C, Potent Neuroprotective Carboxamides from the Appalachian Coal Fire-Associated Isolate Streptomyces sp. RM-14-6

The isolation and structure elucidation of six new bacterial metabolites [spoxazomicin D (2), oxachelins B and C (4, 5), and carboxamides 6–8] and 11 previously reported bacterial metabolites (1, 3, 9–12a, and 14–18) from Streptomyces sp. RM-14-6 is reported. Structures were elucidated on the basis...

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Udgivet i:J Nat Prod
Main Authors: Shaaban, Khaled A., Saunders, Meredith A., Zhang, Yinan, Tran, Tuan, Elshahawi, Sherif I., Ponomareva, Larissa V., Wang, Xiachang, Zhang, Jianjun, Copley, Gregory C., Sunkara, Manjula, Kharel, Madan K., Morris, Andrew J., Hower, James C., Tremblay, Matthew S., Prendergast, Mark A., Thorson, Jon S.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337259/
https://ncbi.nlm.nih.gov/pubmed/28029795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.6b00948
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