Identification of Neuroprotective Spoxazomicin and Oxachelin Glycosides via Chemoenzymatic Glycosyl-Scanning

The assessment of glycosyl-scanning to expand the molecular and functional diversity of metabolites from the underground coal mine fire-associated Streptomyces sp. RM-14-6 is reported. Using the engineered glycosyltransferase OleD Loki and a 2-chloro-4-nitrophenylglycoside-based screen, six metaboli...

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Udgivet i:J Nat Prod
Main Authors: Zhang, Jianjun, Hughes, Ryan R., Saunders, Meredith A., Elshahawi, Sherif I., Ponomareva, Larissa V., Zhang, Yinan, Winchester, Sydney R., Scott, Samantha A., Sunkara, Manjula, Morris, Andrew J., Prendergast, Mark A., Shaaban, Khaled A., Thorson, Jon S.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337260/
https://ncbi.nlm.nih.gov/pubmed/28029796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.6b00949
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