Identification of Neuroprotective Spoxazomicin and Oxachelin Glycosides via Chemoenzymatic Glycosyl-Scanning

The assessment of glycosyl-scanning to expand the molecular and functional diversity of metabolites from the underground coal mine fire-associated Streptomyces sp. RM-14-6 is reported. Using the engineered glycosyltransferase OleD Loki and a 2-chloro-4-nitrophenylglycoside-based screen, six metaboli...

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Detalhes bibliográficos
Publicado no:J Nat Prod
Main Authors: Zhang, Jianjun, Hughes, Ryan R., Saunders, Meredith A., Elshahawi, Sherif I., Ponomareva, Larissa V., Zhang, Yinan, Winchester, Sydney R., Scott, Samantha A., Sunkara, Manjula, Morris, Andrew J., Prendergast, Mark A., Shaaban, Khaled A., Thorson, Jon S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337260/
https://ncbi.nlm.nih.gov/pubmed/28029796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.6b00949
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