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Adverse drug reactions triggered by the common HLA-B*57:01 variant: a molecular docking study
BACKGROUND: Human leukocyte antigen (HLA) surface proteins are directly involved in idiosyncratic adverse drug reactions. Herein, we present a structure-based analysis of the common HLA-B*57:01 variant known to be responsible for several HLA-linked adverse effects such as the abacavir hypersensitivi...
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| Publicado no: | J Cheminform |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5337232/ https://ncbi.nlm.nih.gov/pubmed/28303164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13321-017-0202-6 |
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