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Lipid Desaturation Is a Metabolic Marker and Therapeutic Target of Ovarian Cancer Stem Cells

Lack of sensitive single-cell analysis tools has limited the characterization of metabolic activity in cancer stem cells. By hyperspectral stimulated Raman scattering imaging of single living cells and mass spectrometry analysis of extracted lipids, we report here significantly increased levels of u...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Li, Junjie, Condello, Salvatore, Thomes-Pepin, Jessica, Ma, Xiaoxiao, Xia, Yu, Hurley, Thomas D., Matei, Daniela, Cheng, Ji-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337165/
https://ncbi.nlm.nih.gov/pubmed/28041894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.11.004
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