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A Novel ALDH1A1 Inhibitor Targets Cells with Stem Cell Characteristics in Ovarian Cancer

A small of population of slow cycling and chemo-resistant cells referred to as cancer stem cells (CSC) have been implicated in cancer recurrence. There is emerging interest in developing targeted therapeutics to eradicate CSCs. Aldehyde-dehydrogenase (ALDH) activity was shown to be a functional mark...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Nwani, Nkechiyere G., Condello, Salvatore, Wang, Yinu, Swetzig, Wendy M., Barber, Emma, Hurley, Thomas, Matei, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521036/
https://ncbi.nlm.nih.gov/pubmed/30965686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11040502
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