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Chronic lymphocytic leukaemia

Chronic lymphocytic leukaemia (CLL) is a malignancy of CD5(+) B cells that is characterized by the accumulation of small, mature-appearing lymphocytes in the blood, marrow and lymphoid tissues. Signalling via surface immunoglobulin, which constitutes the major part of the B cell receptor, and severa...

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Detalhes bibliográficos
Publicado no:Nat Rev Dis Primers
Main Authors: Kipps, Thomas J., Stevenson, Freda K., Wu, Catherine J., Croce, Carlo M., Packham, Graham, Wierda, William G., O’Brien, Susan, Gribben, John, Rai, Kanti
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336551/
https://ncbi.nlm.nih.gov/pubmed/28102226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrdp.2016.96
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