Radiation Dosimetry of a Novel Adenosine A(2A) Receptor Radioligand [(11)C]Preladenant Based on PET/CT Imaging and Ex Vivo Biodistribution in Rats

PURPOSE: [(11)C]Preladenant was developed as a novel adenosine A(2A) receptor PET radioligand. The aim of this study was to determine the radiation dosimetry of [(11)C]preladenant and to investigate whether dosimetry estimation based on organ harvesting can be replaced by positron emission tomograph...

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Udgivet i:Mol Imaging Biol
Main Authors: Zhou, Xiaoyun, Elsinga, Philip H., Khanapur, Shivashankar, Dierckx, Rudi A. J. O., de Vries, Erik F. J., de Jong, Johan R.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336543/
https://ncbi.nlm.nih.gov/pubmed/27539309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-016-0992-3
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