Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer

BACKGROUND: While high-risk mutations in identified major susceptibility genes (DNA mismatch repair genes and MUTYH) account for some familial aggregation of colorectal cancer, their population prevalence and the causes of the remaining familial aggregation are not known. METHODS: We studied the fam...

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Bibliografiset tiedot
Julkaisussa:Cancer Epidemiol Biomarkers Prev
Päätekijät: Win, Aung Ko, Jenkins, Mark A., Dowty, James G., Antoniou, Antonis C., Lee, Andrew, Giles, Graham G., Buchanan, Daniel D., Clendenning, Mark, Rosty, Christophe, Ahnen, Dennis J., Thibodeau, Stephen N., Casey, Graham, Gallinger, Steven, Le Marchand, Loïc, Haile, Robert W., Potter, John D., Zheng, Yingye, Lindor, Noralane M., Newcomb, Polly A., Hopper, John L., MacInnis, Robert J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336409/
https://ncbi.nlm.nih.gov/pubmed/27799157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-16-0693
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