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Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer

BACKGROUND: While high-risk mutations in identified major susceptibility genes (DNA mismatch repair genes and MUTYH) account for some familial aggregation of colorectal cancer, their population prevalence and the causes of the remaining familial aggregation are not known. METHODS: We studied the fam...

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Bibliografske podrobnosti
izdano v:Cancer Epidemiol Biomarkers Prev
Main Authors: Win, Aung Ko, Jenkins, Mark A., Dowty, James G., Antoniou, Antonis C., Lee, Andrew, Giles, Graham G., Buchanan, Daniel D., Clendenning, Mark, Rosty, Christophe, Ahnen, Dennis J., Thibodeau, Stephen N., Casey, Graham, Gallinger, Steven, Le Marchand, Loïc, Haile, Robert W., Potter, John D., Zheng, Yingye, Lindor, Noralane M., Newcomb, Polly A., Hopper, John L., MacInnis, Robert J.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336409/
https://ncbi.nlm.nih.gov/pubmed/27799157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-16-0693
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