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Monoclonal antibodies specific for Bacteroides fragilis enterotoxins BFT1 and BFT2 and their use in immunoassays

We have developed 22 mouse IgG(1) monoclonal antibodies (mAbs) against Bacteroides fragilis zinc metalloprotease toxins 1 and 2 (BFT1 and BFT2). Mice were immunized with recombinant BFT1 or BFT2 proteins with metalloprotease activity. Eight of the mAbs bind specifically to BFT1. One mAb, 2H6, binds...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Mootien, Saraspadee, Kaplan, Paul M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336258/
https://ncbi.nlm.nih.gov/pubmed/28257448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173128
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