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Monoclonal antibodies specific for Bacteroides fragilis enterotoxins BFT1 and BFT2 and their use in immunoassays

We have developed 22 mouse IgG(1) monoclonal antibodies (mAbs) against Bacteroides fragilis zinc metalloprotease toxins 1 and 2 (BFT1 and BFT2). Mice were immunized with recombinant BFT1 or BFT2 proteins with metalloprotease activity. Eight of the mAbs bind specifically to BFT1. One mAb, 2H6, binds...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Mootien, Saraspadee, Kaplan, Paul M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336258/
https://ncbi.nlm.nih.gov/pubmed/28257448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173128
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