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Residues in the RecQ C-terminal Domain of the Human Werner Syndrome Helicase Are Involved in Unwinding G-quadruplex DNA

The structural and biophysical properties typically associated with G-quadruplex (G4) structures render them a significant block for DNA replication, which must be overcome for cell division to occur. The Werner syndrome protein (WRN) is a RecQ family helicase that has been implicated in the efficie...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Ketkar, Amit, Voehler, Markus, Mukiza, Tresor, Eoff, Robert L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336152/
https://ncbi.nlm.nih.gov/pubmed/28069813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.767699
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