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A Hdac1/Rpd3-poised circuit balances continual self-renewal and rapid restriction of developmental potential during asymmetric stem cell division

How the developmental potential of differentiating stem cell progeny becomes rapidly and stably restricted following asymmetric stem cell division is unclear. In the fly larval brain, earmuff (erm) uniquely functions to restrict the developmental potential of intermediate neural progenitors (INPs) g...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Janssens, Derek H., Hamm, Danielle C., Anhezini, Lucas, Xiao, Qi, Siller, Karsten H., Siegrist, Sarah E., Harrison, Melissa M., Lee, Cheng-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336133/
https://ncbi.nlm.nih.gov/pubmed/28245922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.01.014
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